New “Superbug” Gene Found in People and Pigs in China Makes Bacteria Antibiotic-Resistant

Scientists in China have made the “alarming” discovery that another line of defense against infection may have been breached.  In research studies led by Hua Liu from the South China Agricultural University, they have identified infectious bacteria that may be resistant to antibiotics.

The University published their work in the Lancet Infectious Diseases journal finding the gene called mcr-1, on plasmids – mobile DNA that can be easily copied and transferred between different bacteria.

According to several news reports, these untreatable superbugs originated in animals before spreading to humans and are highly resistant to antibiotics known as polymyxins, our last line of defense against disease when all else fails.

They include E.coli, the pneumonia bug Klebsiella pneumoniae, and Pseudomonas aeruginosa which can trigger serious lung, blood, and surgical infections.

Professor Nigel Brown, president of Britain’s Microbiology Society, said: “This discovery that resistance to polymyxins can be transferred between bacteria is alarming.

“Now that it has been demonstrated that resistance can be transferred between bacteria and across bacterial species, another line of defense against infection is in danger of being breached.

“We need careful surveillance to track the potential global spread of this resistance, and investment in research to discover new drugs with different modes of action.”

According to  Reuters, researchers warned that these findings suggest “the progression from extensive drug resistance to pandrug resistance is inevitable.”

“(And) although currently confined to China, mcr-1 is likely to emulate other resistance genes … and spread worldwide.”