What you need to know about the coronavirus right now

(Reuters) – Here’s what you need to know about the coronavirus right now:

Sydney’s outbreak throws spotlight on vaccine rollout

Australia’s New South Wales state on Friday reported its biggest daily rise in new COVID-19 cases this year, prompting a tighter lockdown in Sydney and a request for additional vaccine doses that was rebuffed by other state leaders.

Australia reported another record day for vaccination with almost 200,000 doses delivered in one day. Prime Minister Scott Morrison, who on Thursday apologized for the slow pace of inoculation, said the latest data signaled the country’s vaccination rollout had turned a corner.

New Zealand will pause its quarantine-free travel arrangement with Australia for at least eight weeks starting Friday night, Prime Minister Jacinda Ardern said.

Philippines to bar travel from Malaysia, Thailand

The Philippines will suspend travel from Malaysia and Thailand, as well as tighten restrictions in the Manila area, in a bid to prevent the spread of the contagious Delta variant of the coronavirus, the presidential spokesperson said on Friday.

The travel restriction will take effect from Sunday and run to the end of July.

Vietnam’s Ho Chi Minh City extends lockdown

Vietnam will extend a strict lockdown in Ho Chi Minh City until Aug. 1, state media reported on Friday.

After successfully containing the virus for much of the pandemic, Vietnam has been facing a complicated outbreak of the virus, with southern business hub Ho Chi Minh City and surrounding provinces accounting for most new infections.

Banking and securities services in the city will be reduced to minimal levels, while unnecessary construction projects will be suspended.

Taiwan to ease restrictions as cases drop

Taiwan will ease its COVID-19 restrictions next week, the government said on Friday, as rapidly falling case numbers give authorities confidence to further lower the alert level.

Taiwan imposed restrictions on gatherings, including closing entertainment venues and limiting restaurants to take-out service, in mid-May following a spike in domestic cases after months of no or few cases apart from imported ones.

While some of those curbs were eased this month, the so-called level 3 alert has been in force and is due to end on July 26.

Pfizer says U.S. govt buying 200 mln more doses

Pfizer and German partner BioNTech said on Friday the U.S. government had purchased 200 million additional doses of their COVID-19 vaccine and had the option to buy an updated version of the vaccine targeting new variants of the virus.

The announcement brings the total number of the doses to be supplied to the United States to 500 million, out of which roughly 208 million doses have already been delivered.

A longer gap between doses of Pfizer’s vaccine leads to higher overall antibody levels than a shorter gap, a British study found on Friday, but there is a sharp drop in antibody levels after the first dose.

Sinopharm’s shot offers weaker protection among elderly

Sinopharm’s COVID-19 vaccine was less effective in offering protection against the disease among the elderly, according to the results of a Hungarian study.

The study of 450 participants who had received two doses of the vaccine showed measurable antibody levels were present in about 90% of people under the age of 50, but the protection reduced as age increased.

(Compiled by Linda Noakes; Editing by Joe Bavier)

U.S. signs $450 million contract with Regeneron for COVID-19 therapy

By Manojna Maddipatla

(Reuters) – The U.S. government signed a $450 million contract with Regeneron Pharmaceuticals Inc for its potential COVID-19 antibody cocktail, the drug maker said on Tuesday.

The agreement, the first by the Trump administration to support a therapy, comes under the government’s “Operation Warp Speed” program that is aimed at faster distribution of vaccines and treatments to fight the new coronavirus when trials are successful.

The United States is also funding manufacturing and several trials for potential vaccines and has rushed to secure billions of doses of the vaccines being tested by companies around the world.

Earlier in the day, Novavax Inc received a $1.6 billion grant, the biggest award yet from Operation Warp Speed, to cover testing, manufacturing and sale of a potential coronavirus vaccine.

Under the contract with Regeneron, signed with the HHS’ Biomedical Advanced Research and Development Authority and the Department of Defense, the doses manufactured under the project will be owned by the federal government.

Regeneron’s cocktail, REGN-COV2, contains an antibody made by the company and another isolated from recovered COVID-19 patients. Rivals Eli Lilly and AbbVie are also pursuing antibody therapies for the respiratory illness.

REGN-COV2 is being tested separately for both preventing and treating COVID-19, with a late-stage prevention trial being run jointly with the National Institutes of Health.

The agreement covers a fixed number of bulk lots intended to be completed in the fall of 2020, Regeneron said.

A range of 70,000 to 300,000 potential treatment doses or 420,000 to 1,300,000 prevention doses are expected to be available from these lots, with initial doses to be ready as early as end of summer.

The U.S. government would make the doses available to Americans at no cost, if EUA or product approval is granted, Regeneron said.

Shares of Regeneron were up 1.4% at $636.11. They have risen 67% so far this year.

(Reporting by Manojna Maddipatla in Bengaluru; Editing by Shinjini Ganguli)