Cancer overtakes heart disease as biggest rich-world killer

FILE PHOTO: Cancer cells are seen on a large screen connected to a microscope at the CeBit computer fair in Hanover, Germany, March, 6, 2012. REUTERS/Fabian Bimmer/File Photo

LONDON (Reuters) – Cancer has overtaken heart disease as the leading cause of death in wealthy countries and could become the world’s biggest killer within just a few decades if current trends persist, researchers said on Tuesday.

Publishing the findings of two large studies in The Lancet medical journal, the scientists said they showed evidence of a new global “epidemiologic transition” between different types of chronic disease.

While cardiovascular disease remains, for now, the leading cause of mortality worldwide among middle-aged adults – accounting for 40% of all deaths – that is no longer the case in high-income countries, where cancer now kills twice as many people as heart disease, the findings showed.

“Our report found cancer to be the second most common cause of death globally in 2017, accounting for 26% of all deaths. But as (heart disease) rates continue to fall, cancer could likely become the leading cause of death worldwide, within just a few decades,” said Gilles Dagenais, a professor at Quebec’s Laval University in Canada who co-led the work.

Of an estimated 55 million deaths in the world in 2017, the researchers said, around 17·7 million were due to cardiovascular disease – a group of conditions that includes heart failure, angina, heart attack and stroke.

Around 70% of all cardiovascular cases and deaths are due to modifiable risks such as high blood pressure, high cholesterol, diet, smoking and other lifestyle factors.

In high-income countries, common treatment with cholesterol-lowering statins and blood-pressure medicines have helped bring rates of heart disease down dramatically in the past few decades.

Dagenais’ team said their findings suggest that the higher rates of heart-disease deaths in low-income countries may be mainly due to a lower quality of healthcare.

The research found first hospitalization rates and heart disease medication use were both substantially lower in poorer and middle-income countries than in wealthy ones.

The research was part of the Prospective Urban and Rural Epidemiologic (PURE) study, published in The Lancet and presented at the ESC Congress in Paris.

Countries analyzed included Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, India, Iran, Malaysia, Pakistan, Palestine, Philippines, Poland, Saudi Arabia, South Africa, Sweden, Tanzania, Turkey, United Arab Emirates and Zimbabwe.

(Reporting by Kate Kelland, editing by Gareth Jones)

Study finds cosmic rays increased heart risks among astronauts

Astronaut Edwin E. Aldrin Jr., lunar module pilot, walks on the surface of the moon near the leg of the Lunar Module (LM) "Eagle" during the Apollo 11 extravehicular activity (EVA in this NASA handout photo

By Irene Klotz

CAPE CANAVERAL, Fla. (Reuters) – Apollo astronauts who ventured to the moon are at five times greater risk of dying from heart disease than shuttle astronauts, U.S. researchers said on Thursday, citing the dangers of cosmic radiation beyond the Earth’s magnetic field.

The study by researchers at Florida State University and NASA found that three Apollo astronauts, including Neil Armstrong, the first person to walk on the moon, or 43 percent of those studied, died from cardiovascular disease, a finding with implications for future human travel beyond Earth.

The research, published in the journal Scientific Reports, was the first to look at the mortality of Apollo astronauts, the only people so far to travel beyond a few hundred miles (km) of Earth.

It found that the chief health threat to the Apollo astronauts came from cosmic rays, which are more prevalent and powerful beyond the magnetic bubble that surrounds Earth.

NASA disputed the findings, saying it was too early to draw conclusions about the effect of cosmic rays on Apollo astronauts because the current data is limited.

The results of the study have implications for the United States and other countries, as well as private companies, such as Elon Musk’s SpaceX, which are planning missions to Mars and other destinations beyond Earth.

For the study, the researchers examined the death records of 42 astronauts who flew in space, including seven Apollo veterans, and 35 astronauts who died without ever going into space.

They found the Apollo astronauts’ mortality rate from cardiovascular disease was as much as five times higher than for astronauts who never flew, or for those who flew low-altitude missions aboard the space shuttle that orbited a few hundred miles above Earth.

A companion study simulated weightlessness and radiation exposure in mice and showed that radiation exposure was far more threatening to the cardiovascular system than other factors, lead scientist Michael Delp said in an interview.

“What the mouse data show is that deep space radiation is harmful to vascular health,” he said.

So far, only 24 astronauts have flown beyond Earth’s protective magnetic shield, in missions spanning a four-year period from December 1968 to December 1972.

Of those, eight have died, seven of whom were included in the study. The cause of death of the eighth astronaut, Apollo 14’s Edgar Mitchell, who died in February 2016, has not been released, so he was excluded from the study, Delp said. Mitchell was the sixth person to walk on the moon.

Delp and colleagues are working on a follow-up study that includes more detail on family medical histories, smoking and other factors.

(Reporting by Irene Klotz; Editing by Julie Steenhuysen and Peter Cooney)