Britain hopes Christmas can be saved as COVID cases flatten

LONDON (Reuters) – Britain could ease stringent COVID-19 rules to allow families to gather for Christmas as signs indicate that coronavirus cases are starting to flatten as a result of current lockdowns, Health Secretary Matt Hancock said on Friday.

The United Kingdom has the worst official COVID-19 death toll in Europe and Prime Minister Boris Johnson has imposed some of the most stringent curbs in peacetime history in an attempt to halt the spread of the coronavirus.

But heading into the holiday season, the government faces a dilemma – to ease restrictions, with the risk of renewed spread of the disease and death, or to ban large get-togethers.

“It of course won’t be like a normal Christmas, there will have to be rules in place,” Hancock told Sky News.

He said he hoped that restrictions, which include a strict lockdown in England, could be eased to “allow for a bit more of that normal Christmas that people really look forward to”.

Hancock said he was working with the devolved administrations in Scotland, Wales and Northern Ireland – which manage their own policies on combating the pandemic – for a UK-wide approach to rules for Christmas.

The head of London’s Metropolitan Police, Cressida Dick, said that while police might try to stop wild parties, there were better uses of police time than trying to catch families out.

“Let’s see what the rules are, but I have no interest in interrupting family Christmas dinners,” she told LBC radio.

There was some sign that infection numbers were flattening. The Office for National Statistics said incidence had levelled off in recent weeks, with daily infections increasing by 38,900 in England in the latest week, down from around 50,000 previously.

The government also reduced their estimate of the reproduction “R” number, and said the daily growth rate had fallen to between 0% and 2%.

England has been under lockdown for two weeks. It is due to end on Dec. 2, although ministers have not ruled out that it could be extended.

Scotland’s biggest city Glasgow and parts of the nation’s west and central regions begin a stricter lockdown regime on Friday to last until Dec. 11, including the closure of pubs and restaurants and non-essential shops.

(Reporting by Alistair Smout, Sarah Young, Kate Holton and Michael Holden, editing by Guy Faulconbridge and Angus MacSwan)

Europe COVID death toll tops 300,000 as winter looms and infections surge

By Shaina Ahluwalia, Anurag Maan and Roshan Abraham

(Reuters) – More than 300,000 people have died of COVID-19 across Europe, according to a Reuters tally on Tuesday, and authorities fear that fatalities and infections will continue to rise as the region heads into winter despite hopes for a new vaccine.

With just 10% of the world’s population, Europe accounts for almost a quarter of the 1.2 million deaths globally, and even its well-equipped hospitals are feeling the strain.

After achieving a measure of control over the pandemic with broad lockdowns earlier this year, case numbers have surged since the summer and governments have ordered a second series of restrictions to limit social contacts.

In all, Europe has reported some 12.8 million cases and about 300,114 deaths. Over the past week, it has seen 280,000 cases a day, up 10% from the week earlier, representing just over half of all new infections reported globally.

Hopes have been raised by Pfizer Inc’s announcement of a potentially effective new vaccine, but it is not expected to be generally available before 2021 and health systems will have to cope with the winter months unaided.

Britain, which has imposed a fresh lockdown in England, has the highest death toll in Europe at around 49,000, and health experts have warned that with a current average of more than 20,000 cases daily, the country will exceed its “worst case” scenario of 80,000 deaths.

France, Spain, Italy and Russia have also reported hundreds of deaths a day and together, the five countries account for almost three quarters of the total fatalities.

Already facing the prospect of a wave of job losses and business failures, governments across the region have been forced to order control measures including local curfews, closing non-essential shops and restricting movement.

France, the worst-affected country in the EU, has registered more than 48,700 infections per day over the past week and the Paris region’s health authority said last week that 92% of its ICU capacity was occupied.

Facing similar pressures, Belgian and Dutch hospitals have been forced to send some severely ill patients to Germany.

In Italy, which became a global symbol of the crisis when army trucks were used to transport the dead during the early months of the pandemic, daily average new cases are at a peak at more than 32,500. Deaths have been rising by more than 320 per day over the past three weeks.

While the new vaccine being developed by Pfizer and German partner BioNTech will take time to arrive, authorities are hoping that once winter is passed, it will stem further outbreaks next year.

Citi Private Bank analysts described the news as “the first major advance toward a Post-COVID world economy”.

“More than any fiscal spending package or central bank lending program, a healthcare solution to COVID has the greatest potential to restore economic activity to its full potential…” it said in a note.

European Commission President Ursula von der Leyen on Monday said the European Union would soon sign a contract for 300 million doses of the vaccine, just hours after the drugmaker announced promising late-stage trials.

Yet health experts cautioned that the vaccine, should it be approved, was no silver bullet – not least because the genetic material it’s made from needs to be stored at temperatures of minus 70 degrees Celsius (-94 F) or below.

Such requirements pose a challenge for countries in Asia, as well as Africa and Latin America, where intense heat is often compounded by poor infrastructure.

(Reporting by Anurag Maan, Shaina Ahluwalia, Chaithra J and Roshan Abraham in Bengaluru, Sujata Rao-Coverley in London; editing by Jane Wardell, James Mackenzie, Nick Macfie and Mike Collett-White)

In COVID-19 clampdown, China bars travelers from Britain, France, India

BEIJING (Reuters) – China has barred non-Chinese travelers from Britain, France, Belgium, the Philippines and India, imposing some of the most stringent entry curbs of any country as coronavirus cases surge around the world.

The restrictions, which cover those with valid visas and residence permits and take effect in conjunction with a more restrictive testing regime for arrivals from several other countries, drew a frosty response from Britain.

“We are concerned by the abruptness of the announcement and the blanket ban on entry, and await further clarification on when it will be lifted,” said the British Chamber of Commerce in China as the blanket bans were announced by the five countries’ Chinese embassies.

England started a month-long lockdown on Thursday. Britain’s virus death toll is the highest in Europe, and it is grappling with more than 20,000 new cases a day.

Belgium has Europe’s highest per capita number of new confirmed cases, while France and India are among the top five countries in the world with the most infections.

The suspensions were a partial reversal of an easing on Sept. 28, when China allowed all foreigners with valid residence permits to enter. In March, China had banned entry of foreigners in response to the epidemic.

‘SOLD OUT IN SECONDS’

Meanwhile, many people planning November visits to China scrambled to book earlier flights to circumvent potentially disruptive restrictions due to come into force for other countries from Friday.

Linyi Li, a Chinese national, had planned to fly from Seattle to China in mid-November but switched her flight to Nov. 6 even though fares had tripled.

“The tickets were sold out in seconds, as people were all scrambling to beat the deadline,” said Li, 30. “I’ve been rushing to sell many of my family belongings in the past days in case I can’t get back to the States.”

From Friday, all passengers from the United States, France, Germany and Thailand bound for mainland China must take a nucleic acid test and a blood test for antibodies against the coronavirus no more than 48 hours before boarding.

Flights scheduled for Friday are not covered by the new rule, since passengers would have done their tests before that day under previous requirements.

China also plans to impose dual-test requirements on travelers from Australia, Singapore and Japan from Nov. 8.

The European Union Chamber of Commerce in China said the antibody test was not widely available in many countries.

“(So) unfortunately, while technically leaving the door open, these changes imply a de facto ban on anyone trying to get back to their lives, work and families in China,” said the European Union Chamber of Commerce in China.

On Tuesday, China Southern Airlines, the country’s biggest carrier by passenger load, said it would suspend transit services for passengers embarking from 21 countries, mostly African and Asian countries and including India and the Philippines.

The number of weekly international passenger flights serving mainland China from late October through March is set to slump 96.8% from a year earlier to 592, the latest schedules show.

(Reporting by Ryan Woo, Lusha Zhang, Dominique Patton, Stella Qiu, Gabriel Crossley, Martin Pollard and Shivani Singh; Editing by Jacqueline Wong and John Stonestreet)

Britain prepares for COVID-19 vaccine as Oxford forecasts result this year

By Alistair Smout and Guy Faulconbridge

LONDON (Reuters) – Late-stage trial results of a potential COVID-19 vaccine being developed by the University of Oxford and AstraZeneca could be presented this year as the British government prepares for a possible vaccination rollout in late December or early 2021.

A vaccine is seen as a game-changer in the battle against the coronavirus, which has killed more than 1.2 million people worldwide, shuttered swathes of the global economy and turned normal life upside down for billions of people.

There are more than 200 candidates under development and the vaccine being developed by Oxford and licensed to British drugmaker AstraZeneca is seen as a front-runner.

“I’m optimistic that we could reach that point before the end of this year,” Oxford Vaccine Trial Chief Investigator Andrew Pollard said of the chances of presenting trial results.

Pollard told British lawmakers that establishing whether or not the vaccine worked would likely come this year, after which the data would have to be carefully reviewed by regulators and then a political decision made on who should receive it.

“Our bit – we are getting closer to but we are not there yet,” Pollard, director of the Oxford Vaccine Group, said.

Asked if he expected the vaccine would start to be deployed before Christmas, he said: “There is a small chance of that being possible but I just don’t know.”

The National Health Service (NHS) in England is preparing to start distributing possible COVID-19 vaccines before Christmas in case one is ready by the end of the year.

The Oxford/AstraZeneca vaccine is expected to be one of the first from big pharma to be submitted for regulatory approval, along with Pfizer and BioNTech’s candidate.

“If I put on my rose-tinted specs, I would hope that we will see positive interim data from both Oxford and from Pfizer/BioNTech in early December and if we get that then I think we have got the possibility of deploying by the year end,” Kate Bingham, the chair of the UK Vaccine Taskforce, told lawmakers.

Prime Minister Boris Johnson said there was the prospect of a vaccine in the first quarter of 2021. AstraZeneca is presenting its third quarter financial results on Thursday.

‘GAME CHANGER’

Work on the Oxford viral vector vaccine, called AZD1222 or ChAdOx1 nCoV-19, began in January. It is made from a weakened version of a common cold virus that causes infections in chimpanzees.

The chimpanzee cold virus has been genetically changed to include the genetic sequence of the so-called spike protein which the coronavirus uses to gain entry to human cells. The hope is that the human body will then attack the novel coronavirus if it sees it again.

If Oxford’s vaccine works, it could eventually allow the world to return to some measure of normality.

Asked what success looked like, Pollard said: “Good is having vaccines that have significant efficacy – so whether, I mean, that is 50, 60, 70, 80 percent, whatever the figure is – is an enormous achievement.

“It’s a complete game changer and a success if we meet those efficacy end points,” he said, adding it would relieve pressure on the health system.

But Pollard and Bingham agreed that the world would not return to normal immediately. Asked about the chances of a vaccine that would wipe out the coronavirus next year, Bingham said the prospects were “very slim.”

“(But the chances) to get a vaccine that has an effect of both reducing illness, and reducing mortality (are) very high,” Bingham said, adding she was more than 50% confident there would be such a vaccine by early summer.

(Reporting by Alistair Smout and Guy Faulconbridge; Editing by Nick Macfie and Alexander Smith)

Terrorism threat level in Britain raised to ‘severe’

LONDON (Reuters) – Britain’s terrorism threat level has been raised to ‘severe’ as a precaution following attacks in France and Austria, interior minister Priti Patel said on Tuesday.

The change, which means an attack is now seen as highly likely, comes the day after a gunman in Vienna identified as a convicted jihadist killed four people in a rampage overnight. France has also suffered three attacks in recent weeks.

“This is a precautionary measure following the terrible instances that we’ve seen in France last week, and the events that we saw in Austria last night,” Patel said in a televised statement

She said the public should not be alarmed and that the change in threat level was not based on any specific threat.

The new threat level means an attack is highly likely, according to the government’s classification system. The previous ‘substantial’ level meant an attack was likely.

Britain’s threat level is assessed by the Joint Terrorism Analysis Centre which is accountable to the domestic intelligence agency MI5 and made up of representatives from 16 government departments and agencies.

(Reporting by William James and David Milliken; editing by Stephen Addison)

IMF tells G20 countries to “keep spending” on COVID-19 crisis

By Andrea Shalal

WASHINGTON (Reuters) – The International Monetary Fund on Monday warned Group of 20 major economies that the coronavirus crisis is not over and called on the United States, Britain and other countries to increase the amount of fiscal spending currently planned.

Premature withdrawal of fiscal support at a time of continued high rates of unemployment would “impose further harm on livelihoods and heighten the likelihood of widespread bankruptcies, which in turn could jeopardize the recovery,” senior IMF officials warned in a blog published Monday.

The blog, entitled, “The Crisis is Not Over, Keep Spending (Wisely),” said swift and unprecedented action by G20 and emerging market economies had averted an even deeper crisis, with G20 countries alone providing $11 trillion in support.

The IMF last month forecast a 2020 global contraction of 4.4% and a return to growth of 5.2% in 2021, but warned that the situation remained dire and governments should not withdraw stimulus prematurely.

On Monday, it said COVID infections were continuing to spread, but much of the fiscal support provided was now winding down, with cash transfers to households, deferred tax payments and temporary loans to businesses either having expired or being set to do so by year-end.

In economies where deficits dropped by 10% of gross domestic product this year, fiscal balances are expected to narrow by more than 5% of GDP in 2021, largely due to a sharp withdrawal of relief measures, they said.

“Larger support than currently projected is desirable next year in some economies,” the IMF said in a longer report to G20 countries also published Monday. It singled out Brazil, Mexico, Britain and the United States, citing large drops in employment in these economies and projected fiscal contractions.

Democratic lawmakers and Republican President Donald Trump have been unable to reach agreement on a new stimulus package for the United States, the world’s largest economy. New spending may not be agreed until early 2021, depending on the outcome of the presidential election on Tuesday.

The IMF said countries should maintain support for poor and vulnerable groups hit disproportionately hard by the crisis, as well as targeted support for viable firms to maintain employment relationships. It listed India, Mexico, Russia, Saudi Arabia, Turkey and the United States as examples.

However it warned against providing support for firms that hindered a transfer of resources from sectors that may permanently shrink to those sectors that will be expanding.

(Reporting by Andrea Shalal; Editing by Chizu Nomiyama and Nick Macfie)

Washington hits Belarus with sanctions as Minsk retaliates against EU measures

(Reuters) – The United States imposed sanctions on eight Belarusian officials on Friday, accusing them of involvement in rigging President Alexander Lukashenko’s re-election victory in August or the violent crackdown on protests that followed.

The move came after the European Union announced sanctions on 40 people, including the interior minister and the head of the election commission, achieving a breakthrough on the issue at summit talks in the early hours of Friday morning.

Lukashenko was spared, in line with the EU’s policy of punishing powerbrokers as a last resort. He denies electoral fraud and says the protests are backed from abroad.

Lukashenko’s government announced retaliatory sanctions against unidentified officials, recalled its ambassadors to Poland and Lithuania for consultations and nudged both countries to reduce the size of their embassy staff in Minsk.

Lukashenko is grappling to contain nearly two months of street protests that pose the biggest challenge to his 26-year rule. More than 13,000 people have been arrested, and major opposition figures jailed or exiled.

“The United States and our international partners stand united in imposing costs on those who have undermined Belarusian democracy for years,” U.S. Treasury Secretary Steven Mnuchin said in a statement.

The U.S. sanctions also targeted Belarusian Interior Minister Yuri Karaev and his deputy. Those under sanctions are subject to asset freezes and a ban against Americans doing business with them.

Washington had originally been expected to impose sanctions in concert with Britain and Canada, which went ahead on Tuesday with travel bans and asset freezes on Lukashenko, his son Viktor and other senior officials.

Washington has had sanctions on Lukashenko since 2006 but the president was spared in the latest round of measures.

LUKASHENKO SPEAKS TO PUTIN

The crisis has pushed Belarus back towards traditional ally Russia, which has propped up Lukashenko’s government with loans and the offer of military support. Moscow sees its ex-Soviet neighbor as a strategic buffer against the EU and NATO.

Lukashenko and Russian President Vladimir Putin spoke by phone on Friday, expressing confidence that “the problems that have arisen will soon be resolved”, the Kremlin said.

Lukashenko’s government announced it had drawn up a list of people who were banned from travelling to Belarus in retaliation for the EU sanctions. It did not name the officials or the countries they were from.

“…we are imposing visa sanctions against the most biased representatives of European institutions, including the European Parliament and the states – EU members,” foreign ministry spokesman Anatoly Glaz was quoted by the official Belta news agency as saying.

“The list is symmetrical in many ways. We have decided not to make it public for now.”

Russia’s foreign ministry said the Belarusian sanctions would apply in Russia as well.

Lukashenko’s government also asked the Polish and Lithuanian embassies to reduce their staff. Both countries refused.

“We are not going to summon our ambassadors for consultations, and we will definitely not do anything to reduce personnel,” Lithuanian Foreign Affairs Minister Linas Linkevicius told reporters.

“We are not interested in reducing our communications channel,” he said. “If the advice becomes a request, then we will take appropriate measures.”

The Belarusian authorities have detained journalists or stripped them of their accreditation as part of the crackdown on the unrest that followed the Aug. 9 election.

On Friday, the foreign ministry announced it was stripping journalists working for foreign media organizations of their accreditation, and asked them to reapply for their permits.

“I would like to make it clear that it is in no way some attempt to cleanse the news reporting field,” Glaz was quoted by Belta as saying.

The EU sanctions had been held up by Cyprus due to an unrelated dispute with Turkey. The delay dented the credibility of the EU’s foreign policy, diplomats said.

“That we could now agree to those sanctions is an important signal because it strengthens the hand of those who are protesting for freedom of opinion in Belarus,” German Chancellor Angela Merkel told journalists.

Merkel will meet on Tuesday with Sviatlana Tsikhanouskaya, Lukashenko’s main electoral opponent who fled into exile after the vote in the ex-Soviet republic, fearing for her family’s safety.

French President Emmanuel Macron met Tsikhanouskaya on Tuesday, pledging European support for the Belarusian people.

(Reporting by Matt Spetalnick, Daphne Psaledakis and Arshad Mohammed in Washington, Robin Emmott in Brussels, Andrius Sytas in Vilnius, Vladimir Soldatkin, Alexander Marrow and Polina Ivanova in Moscow, Joanna Plucinska in Warsaw, Thomas Escritt in Berlin; writing by Matthias Williams; editing by Mark Potter)

Exclusive: New global lab network will compare COVID-19 vaccines head-to-head

By Kate Kelland

LONDON (Reuters) – A major non-profit health emergencies group has set up a global laboratory network to assess data from potential COVID-19 vaccines, allowing scientists and drugmakers to compare them and speed up selection of the most effective shots.

Speaking to Reuters ahead of announcing the labs involved, Melanie Saville, director of vaccine R&D at the Coalition for Epidemic Preparedness Innovations (CEPI), said the idea was to “compare apples with apples” as drugmakers race to develop an effective shot to help control the COVID-19 pandemic.

The centralized network is the first of its kind to be set up in response to a pandemic.

In a network spanning Europe, Asia and North America, the labs will centralize analysis of samples from trials of COVID-19 candidates “as though vaccines are all being tested under one roof”, Saville said, aiming to minimize the risk of variation in results.

“When you start off (with developing potential new vaccines) especially with a new disease, everyone develops their own assays, they all use different protocols and different reagents – so while you get a readout, the ability to compare between different candidates is very difficult,” she told Reuters.

“By taking the centralized lab approach … it will give us a chance to really make sure we are comparing apples with apples.”

The CEPI network will initially involve six labs, one each in Canada, Britain, Italy, the Netherlands, Bangladesh and India, Saville said.

Hundreds of potential COVID-19 vaccines are in various stages of development around the world, with shots developed in Russia and China already being deployed before full efficacy trials have been done, and front-runners from Pfizer, Moderna and AstraZeneca likely to have final-stage trial results before year-end.

Typically, the immunogenicity of potential vaccines is assessed in individual lab analyses, which aim to see whether biomarkers of immune response – such as antibodies and T-cell responses – are produced after clinical trial volunteers receive a dose, or doses, of the vaccine candidate.

But with more than 320 COVID-19 vaccine candidates in the works, Saville said, the many differences in data collection and evaluation methods are an issue.

As well as potential variations in markers of immunity, there are differences in how and where samples are collected, transported and stored – all of which can impact the quality and usefulness of the data produced, and make comparisons tricky.

And with a range of different vaccine technologies being explored – from viral vector vaccines to ones based on messenger RNA – standard evaluation of their true potential “becomes very complex”, she said.

“With hundreds of COVID-19 vaccines in development … it’s essential that we have a system that can reliably evaluate and compare the immune response of candidates currently undergoing testing,” she said.

By centralizing the analysis in a lab network, much of what Saville called the “inter-laboratory variability” can be removed, allowing for head-to-head comparisons.

CEPI says all developers of potential COVID-19 vaccines can use the centralized lab network for free to assess their candidates against a common protocol. For now, the network will assess samples from early-stage vaccine candidate testing and first and second stage human trials, but CEPI said it hoped to expand its capacity to late stage (Phase III) trial data in the coming months.

Results produced by the network will be sent back to the developer, with neither CEPI nor the network owning the data.

CEPI itself is co-funding nine of the potential COVID-19 vaccines in development, including candidates from Moderna, AstraZeneca, Novavax and CureVac.

(Reporting by Kate Kelland, editing by Mark Potter)

Europeans, UK tell U.N. Navalny poisoning a ‘threat to international peace, security’

By Michelle Nichols

NEW YORK (Reuters) – The poisoning of Kremlin critic Alexei Navalny “constitutes a threat to international peace and security,” Britain, France, Germany, Estonia and Belgium wrote in a letter to the United Nations Security Council, seen by Reuters on Thursday.

“We call on the Russian Federation to disclose, urgently, fully and in a transparent manner, the circumstances of this attack and to inform the Security Council in this regard,” they said in the letter sent to the 15-member body late on Wednesday.

Navalny was flown to Berlin in August after falling ill on a Russian domestic flight. He received treatment for what Germany said was poisoning by a potentially deadly nerve agent, Novichok, before being discharged in September.

The letter to the Security Council said that on Sept. 2 the German government confirmed that tests had shown “unequivocal proof that Mr Navalny had been poisoned by a chemical nerve agent from the Novichok group, which was developed by the Soviet Union and subsequently held by its successor state” Russia.

Russia has denied any involvement in the incident and said it has yet to see evidence of a crime. The Russian mission to the United Nations did not have an immediate comment on the letter.

The European members of the Security Council and Britain noted that last November the Security Council adopted a statement reaffirming that any use of chemical weapons “anywhere, at any time, by anyone, under any circumstance is unacceptable and a threat to international peace and security.”

“As such, we consider that the use of a chemical nerve agent from the Novichok group in the abhorrent poisoning of Mr Alexey Navalny constitutes a threat to international peace and security,” they wrote.

The letter was sent as Russia takes the monthly presidency of the Security Council for October.

The United States did not sign the letter, but on Wednesday U.S. Secretary of State Mike Pompeo said: “The Russian Government must provide a full accounting for the poisoning of Alexei Navalny and hold those involved responsible.”

(Reporting by Michelle Nichols; editing by Jonathan Oatis)

No clear link between school opening and COVID surge, study finds

By Kate Kelland

LONDON (Reuters) – Widespread reopening of schools after lockdowns and vacations is generally not linked to rising COVID-19 rates, a study of 191 countries has found, but lockdown closures will leave a 2020 “pandemic learning debt” of 300 billion missed school days.

The analysis, by the Zurich-based independent educational foundation Insights for Education, said 84% of those 300 billion days would be lost by children in poorer countries, and warned that 711 million pupils were still out of school.

“It’s been assumed that opening schools will drive infections, and that closing schools will reduce transmission, but the reality is much more complex,” said IfE’s founder and chief executive Randa Grob-Zakhary.

The vast majority – 92% – of countries that are through their first wave of COVID-19 infections have started to reopen school systems, even as some are seeing a second surge.

IfE found that 52 countries that sent students back to school in August and September – including France and Spain – saw infection rates rise during the vacation compared to when they were closed.

In Britain and Hungary, however, infection levels dropped after initial school closures, remained low during the holidays, and began rising after reopening.

Full analysis of these 52 countries found no firm correlation between school status and infections – pointing to a need to consider other factors, IfE said.

“The key now is to learn from those countries that are reopening effectively against a backdrop of rising infections,” Grob-Zakhary said.

The report said 44 countries have kept schools closed.

It found countries are developing strategies for schools during the pandemic – including some, such as Italy, France, which order temporary school closures on a case-by-case basis.

Other measures include policies on masks, class rotations and combining remote with in-school lessons.

“This first real global test highlights what school life looks like in a COVID-world,” said Grob-Zakhary. “Understanding how countries undergoing a massive second wave are dealing with this new reality in the classroom is essential to guide future reopening decisions and to help schools remain open.”

(Reporting by Kate Kelland; Editing by Giles Elgood)