How sewer science could ease testing pressure and track COVID-19

By Kate Kelland

LONDON (Reuters) – The science of sewage surveillance could be deployed in countries across the world to help monitor the spread of national epidemics of COVID-19 while reducing the need for mass testing, scientists say.

Experts in the field – known as wastewater epidemiology – say that as countries begin to ease pandemic lockdown restrictions, searching sewage for signs of the SARS-CoV-2 coronavirus could help them monitor and respond to flare-ups.

Small early studies conducted by scientific teams in The Netherlands, France, Australia and elsewhere have found signs that the COVID-19-causing virus can be detected in sewage.

“Most people know that you emit lots of this virus through respiratory particles in droplets from the lungs, but what’s less well known is that you actually emit more small virus particles in feces,” said Davey Jones, a professor of environmental science at Britain’s Bangor University.

This suggests that on a wider scale, sewage sampling would be able to estimate the approximate number of people infected in a geographic area without having to test every person.

“Every time a person becomes infected with COVID-19, they start shedding virus into the sewer system,” Jones said. “We’re using that (knowledge) and tracking people’s toilet movements.”

The practice has been used to monitor health threats and viral diseases before.

It’s a crucial tool in the global fight to eradicate polio, and scientists in Britain and elsewhere also use it to monitor antibiotic resistance genes from livestock farming.

“Wastewater epidemiology has been part of monitoring of polio infection across the world, so it’s not completely new,” said Alex Corbishley, a veterinary scientist at the Roslin Institute in Edinburgh who is running a three-month pilot project to track SARS-CoV-2 in wastewater in Scotland. “But it’s never really been applied to an outbreak in this way.”

“The idea here is that you could potentially use this as a relatively cheap, but much more importantly, scaleable, way of saying ‘there’s X amount of transmission’ in a community.”

NOT INFECTIOUS

Scientists conducting initial COVID-19 sewage studies in Europe and Australia stress that what they are picking up is not live, infectious virus, but dead particles or fragments of the virus’s genetic material that are not infectious.

In a pilot trial in Queensland, Australia, scientists were able to detect a gene fragment of SARS-CoV-2 in sewage from two wastewater treatment plants.

In the Netherlands, sewage epidemiologists acted ahead of the COVID-19 outbreak there and took samples from seven cities and a major airport in February and March.

While they found no detectable virus three weeks before the first COVID-19 case was detected, by March 5 – barely a week after the first case was confirmed there – they were able to detect virus fragments.

“The detection of the virus in sewage, even when the COVID-19 prevalence is low, indicates that sewage surveillance could be a sensitive tool to monitor the circulation of the virus,” the researchers wrote in a paper posted online on MedRxiv.

Researchers in Paris posted findings in April that showed how sampling wastewater in the city for a month tracked the same curve of the rising and falling epidemic there.

Few countries have the resources or capacity to test each person individually, with most only able to test healthcare workers or people with symptoms severe enough to mean they need hospitalization. This means authorities have only limited information about how widespread the new coronavirus is or whether it is affecting some communities more than others.

“You can use this type of surveillance as a public health tool,” said Andrew Singer, a researcher at the UK Centre for Ecology and Hydrology who is working with Davey and others on pilot coronavirus sewage testing plans in Britain.

“And the utility of this approach is that it’s so cheap and the investment that you make … will reap rewards, not just for (this) coronavirus pandemic,” but for future outbreaks too.

(Editing by Janet Lawrence)

Truckers hit by coronavirus pandemic face rocky road to recovery

By Karl Plume

CHICAGO (Reuters) – Bryan Hutchens in Oklahoma estimates he’s only used his two flat-bed trucks to shift oilfield equipment for a week out of the past month as the coronavirus crisis shutters businesses.

In New York, trucking firm ERL Intermodal says its cargo volumes have halved as lockdowns sideline its business of moving everything from olive oil to garden hoses to truck parts.

At the world’s busiest border, trucks hauling food and consumer products north to the United States are returning empty to Mexico where mass job losses have hit demand, leaving cash-strapped truckers to log hundreds of costly, empty miles.

The pandemic has turned the global trucking industry on its head. As swathes of the world economy shut down and curbs on movement and gatherings disrupt supply chains, freight companies are hemorrhaging cash and sidelining thousands of truckers.

“Once the economy gets going again, my fear is that there will be so many truckers out of the business by then,” said Steve Sperbeck, general manager for ERL, which has a fleet of 52 trucks based in Utica, New York.

According to the International Road Transport Union (IRU) in Geneva, which represents operators in 80 countries, new freight contracts have declined by 60% to 90% since COVID-19 struck while empty runs have climbed by up to 40%.

For truckers shipping products such as car parts, clothes, flowers and construction materials, operations have ground to an almost complete halt, the IRU said.

Lockdown restrictions in India, the world’s second-most populous country, have sidelined 80% of the 10 million trucks behind a $130 billion industry that hauls 60% of the country’s freight.

In Brazil, which relies on trucks to shift key exports such as soybeans, coffee and sugar to ports, shipments have also slumped. Carlos Litti, director for road transportation at the National Confederation of Transport Workers, said firms were now delaying critical maintenance work such as tire retreading, as government support for the sector had been insufficient.

“At the moment, there is no way to pressure the government,” Litti said. “The economy just has to turn around.”

SMALL CARRIERS VULNERABLE

In March, U.S. freight rates surged on fears the virus and the closure of highway truck stops would discourage drivers from making long trips. But with many factories shut and port traffic down, rates have plummeted as truckers battle over jobs to try to stay afloat through the crisis.

If the pain is prolonged, smaller U.S. carriers that cannot spread their costs across a large fleet could shut their doors, pushing skilled drivers out of the business and accelerating a longer-term shortage of truckers, industry groups say.

Some 97% of trucking companies in the United States operate fewer than 20 trucks, and 91% have six or fewer, according to the American Trucking Associations. Those workers rely more often on one-off jobs than long-term contracts.

Some routes are paying just 75 cents to 80 cents a mile, less than half of what’s needed to pay for fuel, insurance and other operating costs, according to five truckers. Pay is mostly determined by distances driven and they have also dropped.

When energy firms hit by the slump in oil prices stopped giving work to Hutchens in Oklahoma, he parked his rigs instead of rushing, like many other truckers, to haul essential goods such as food and medical equipment at loss-making rates.

Bids in the spot market have crashed to the lowest in years as shuttered factories, schools and malls have left scores of truckers that usually have longer-term contracts searching for new cargo to haul.

“In some lanes, rates are lower now than they were 15 years ago, but all of our costs, from fuel to insurance, have gone up,” Hutchens said.

He has laid off one employee and may have to begin selling his equipment if business does not return to more normal levels in the next two to three months. Relaxed restrictions on driver hours and more transparency on shippers’ margins could help smaller operators compete, Hutchens said.

“We’re a small company. There’s not a whole lot we can cut,” he said. “When we do come back online, we don’t know what the volume is going to be, so we don’t know how quickly things are going to return to normal.”

For an interactive graphic on average U.S. truck freight rates click on: https://tmsnrt.rs/2Z3sgYG

‘WE’RE BEING GOUGED’

ERL Intermodal says it earns more from pre-contracted shipments than spot market loads but revenues for the central New York trucker have also dropped. Six ERL drivers have been furloughed and paychecks for those left have dropped 30% as their hours behind the wheel decline.

To make ends meet, ERL leased nine of its refrigerated trailers to the Department of Homeland Security for use as makeshift morgues for COVID-19 victims. The company also tapped an emergency government loan program to help to pay salaries.

“Financially, it probably wasn’t the best decision, but good drivers are hard to come by,” said ERL’s Sperbeck.

At the Mexico-U.S. border, some truckers are carrying just one full load south for every seven full northbound trips, well below the usual three-to-one ratio, according to data from freight forwarder Nuvocargo.

“We are very concerned that if business does not come back to usual … it’s going to result in things like bankruptcies and losing jobs,” Nuvocargo chief executive Deepak Chhugani said.

Dozens of U.S. truckers parked near the White House in Washington for over a week this month to protest over the low freight rates and industry regulations they say are disproportionately hurting small, independent truckers.

Standing by make-shift shelters, truck driver Mike Landis from Pennsylvania said his workload had dropped by up to 50% since the pandemic struck, and most of the jobs available were being offered at rates below operating costs.

“After being told we’re essential and told by the government to stay out here and basically risk our health to continue moving the things that the country needs, we’re being gouged,” Landis said.

“We’re here as middle-class people, the people that put the president in office, and we’re here asking him for help.”

(Reporting by Karl Plume in Chicago; Additional reporting by Lisa Baertlein in Los Angeles, Alberto Alerigi in Sao Paulo and Emma Farge in Geneva; Editing by Caroline Stauffer and David Clarke)

Pandemic hampers Philippines mass evacuation as typhoon hits

By Karen Lema

MANILA (Reuters) – The coronavirus pandemic is complicating Philippine efforts to move hundreds of thousands of people into evacuation centers where social distancing is hard to enforce as a strong typhoon pummeled through its eastern provinces.

Typhoon Vongfong, the first to hit the country this year, intensified after slamming into the eastern Philippines on Thursday afternoon, packing winds of 155 kilometers per hour (kph) and gusts of up to 255 kph (158 miles per hour), the state weather bureau said in a bulletin.

Provincial and city governments, many of which are already strapped for resources due to the outbreak, are grappling with logistical and space issues, with an estimated 200,000 people needed to be moved from their homes in coastal and mountainous areas because of fears of flooding and landslides.

“This is really a nightmare for us here,” Ben Evardone, governor of the Eastern Samar province, told CNN Philippines. “Our problem right now is where to squeeze our people, while making sure they practice social distancing”.

With an average of 20 typhoons every year hitting the Philippines, an archipelago of more than 7,000 islands, the challenges faced by stretched-thin local governments offer a grim preview of disaster response in the time of COVID-19.

The typhoon was forecast to move northwestward and hit Luzon, the country’s largest island that includes the capital Manila, which remains on lockdown.

Images shared on social media showed the powerful typhoon bringing intense rain and violent winds in areas along its path, toppling trees, knocking out power and destroying homes.

In the town of Buhi in the province of Camarines Sur, hundreds of evacuees were given face masks before they were allowed in the evacuation centers.

Mark Anthony Nazarrea, a public information officer at Buhi, said the local government turned two more schools into temporary shelters to enable better social distancing.

There were no reported cases of the new coronavirus in Buhi, Nazarrea said, but “we want to minimize the risk”.

Classrooms that used to accommodate eight families during disasters are now housing only one to two families, he said.

The novel coronavirus has killed 790 people in the Philippines since the first local transmission was recorded in March, and infected close to 12,000.

(Additional reporting by Neil Jerome Morales; Editing by Mark Potter)

Researchers revise U.S. COVID-19 death forecast upward again

By Steve Gorman

(Reuters) – A newly revised coronavirus mortality model predicts more than 147,000 Americans will die from COVID-19 by early August, up nearly 10,000 from the last projection, as restrictions for curbing the pandemic are relaxed, researchers said on Tuesday.

The latest forecast from the University of Washington’s Institute for Health Metrics and Evaluation (IHME) reflects “key drivers of viral transmission like changes in testing and mobility, as well as easing of distancing policies,” the report said.

The revision reinforced public health warnings, including U.S. Senate testimony on Tuesday from Dr. Anthony Fauci, the nation’s top infectious disease expert, that prematurely lifting lockdowns could lead to more outbreaks of the respiratory virus.

Fauci and other medical experts have urged caution in relaxing restraints on commerce before diagnostic testing and the ability to trace close contacts of infected individuals can be vastly expanded, along with other safeguards.

IHME researchers acknowledged that precise consequences of moves to reopen shuttered businesses and loosen stay-at-home orders are difficult to gauge.

“The full potential effects of recent actions to ease social distancing policies, especially if robust containment measures have yet to be fully scaled up, may not be fully known for a few weeks due to the time periods between viral exposure, possible infection and full disease progression,” the report said.

COVID-19, the respiratory illness caused by the novel coronavirus, has already claimed nearly 81,000 lives in the United States, out of more than 1.36 million known infections, according to a Reuters tally.

The revised IHME model, frequently cited by the White House and other public health authorities, predicted that the cumulative U.S. death toll will climb to 147,040 by Aug. 4, up 9,856 from the institute’s previous update on Sunday.

A week earlier, the model had sharply increased the figure to nearly 135,000 deaths, almost double its April 29 forecast, citing steps in about 30 states to ease social-distancing requirements.

The clamor to reopen businesses ranging from restaurants to auto plants has only gained momentum since then as unemployment hit levels not seen since the Great Depression of the 1930s.

The projections are presented as a range, with the latest forecast – 147,00-plus deaths – representing the average between a best-case scenario of 102,783 lives lost and a worst-case scenario of 223,489 fatalities.

The forecasts have fluctuated over the past couple of months, with a projected death toll as low as 60,000 on April 18.

(Reporting by Steve Gorman in Los Angeles; Editing by Sandra Maler and Cynthia Osterman)

NYC deaths from non-COVID causes rise over 5,000 above normal rate: CDC

Reuters) – The number of deaths in New York City from causes other than COVID-19 rose by more than 5,000 people above the seasonal norm during the first two months of the pandemic, the Centers for Disease Control and Prevention (CDC) said on Monday.

The deaths could be due to several factors, the CDC said, including delays in seeking or getting life-saving care for fear of exposure to the coronavirus.

Tracking excess mortality is vital in understanding the contribution to the death rate of both COVID-19 and poor availability of care for people with non-COVID conditions, noted researchers, who reported their findings in the CDC’s Morbidity and Mortality Weekly Report (MMWR).

The CDC used data from the New York City Department of Health and Mental Hygiene, which has an electronic reporting system with a near complete count of all deaths in the city.

Between March 11 and May 2, 32,107 deaths were reported to the department. Of these, 24,172 were found to be in excess of the seasonal norm. This included 13,831 (57%) laboratory-confirmed COVID-19–associated deaths and 5,048 (21%) probable COVID-19–associated deaths.

That means 5,293, or 22% of the excess deaths, were not identified as being associated with COVID-19.

These deaths could be directly or indirectly attributed to the pandemic and counting only the confirmed or probable COVID-19–associated deaths likely underestimates deaths attributable to the pandemic, the researchers said.

(Reporting by Vishwadha Chander in Bengaluru; Editing by Arun Koyyur)

After surviving wars, pestilence, religions use technology to beat pandemic

By Angela Moore

NEW YORK (Reuters) – Throw a global pandemic at the world’s religions, and you get confessions via Skype, virtual seders and recitations of the Koran over Facebook.

The world’s three leading religions have survived famines, plagues, pestilence and wars. Now, in the 21st century shutdown, New York-area Jewish, Islamic and Christian clerics are turning to technology to help their followers through the coronavirus.

Worshipers have taken to online connections as the dangers of the virus and uncertainty of self-isolation deepen their spirituality and strengthen their faith, the clerics said.

“I think from a spiritual standpoint, it’s very empowering,” said Sheikh Osamah Salhia, Imam at the Islamic Center of Passaic County in Clifton, New Jersey.

The government-ordered shutdowns have been “a chance for us to recognize our real priorities in life and gain a sense of clarity on what really matters: family, community, the masjid (mosque) and its role,” he said in an interview.

While bans on mass gatherings have taken away the communal aspect of prayers, especially during the Muslim fasting month of Ramadan, the Islamic Center is connecting online with congregants for classes and Koran readings, Salhia said.

Livestream prayers, however, are not encouraged, he said, adding families should pray together at home.

VIRTUAL HUGS AND KISSES

This year, many Jews, including Esther Greenberg of New York’s Long Island, gathered their families for Passover on Zoom.

“Unfortunately, we all can’t be together holding each other around, giving hugs and kisses, but we’re doing it virtually because this is what our family does,” Greenberg, 73, said at her April 8 seder.

At the Park East Synagogue in Manhattan, many of the sanctuary’s mostly older congregants have been connecting via the internet for the first time, Cantor Benny Rogosnitzky said.

“Technology has been amazing,” said Rogosnitzky. “It really is a lifeline.

Congregants use online platforms to link not only to morning services but to a supportive community that has grown more spiritual during the crisis, Rogosnitzky said.

After the lockdown, he said he envisions smaller, shorter gatherings, with barriers in the sanctuary and temperature-takers greeting worshipers.

“It’s going to be more about, stay separate,” he said.

Contrary to some polls showing declines in virtual religious attendance since the virus outbreak, the Cathedral Church of Saint John the Divine in Manhattan has seen an increase in online worshipers for its Episcopal services, said the Rev. Patrick Malloy.

“One of the great things that’s happening on Sundays is we have people from all over the world, and thousands of them sharing of worship with us every Sunday,” said Malloy.

“For the first time, I heard a confession by Skype,” he added. “You know, you have to do what you have to do.”

Like other clerics, Malloy says he has seen more spirituality in the flock during the pandemic.

“When you’re locked in your house, and especially when you’re locked in a small New York apartment by yourself, day after day after day, you come to think about the bigger questions,” he said.

When the crisis ends, Malloy said he expects to see the church at least as full as it was before because “people really do miss one another.”

(Writing by Peter Szekely; editing by Bill Tarrant and Sonya Hepinstall)

Turkey turns to medical diplomacy to heal damaged relations

By Tuvan Gumrukcu

ANKARA (Reuters) – Emblazoned with Turkish flags and presidential seals, crates packed with medical equipment are loaded onto planes, part of a major aid campaign by Ankara which has dispatched supplies to dozens of countries since the new coronavirus pandemic erupted.

“There is hope after despair and many suns after darkness,” says a message on every shipment – a line from 13th-century Sufi poet Jalaluddin Rumi, which looks to better days not just in the battle against COVID-19 but also for Turkey’s fraught diplomacy.

With its relations with NATO allies in Europe and the United States darkened by disputes over Russian missile defenses, human rights, and Western sanctions on Iran, Turkey hopes the virus crisis is an opportunity to soothe recent tensions.

Despite battling one of the world’s biggest coronavirus outbreaks at home – where the death toll now exceeds 3,700 -, Turkey has sent medical aid to 61 countries, including the United States, Spain, Italy, France, and Britain.

By its own calculations, Ankara has been the world’s third-biggest aid distributor during the outbreak, sending face masks, protective suits, testing kits, disinfectant, and respirators.

In a letter to President Donald Trump sent with one shipment, President Tayyip Erdogan said he hoped the “spirit of solidarity” Turkey had shown would help U.S. politicians “better understand the strategic importance of our relations”.

Ankara faces potential U.S. sanctions over its purchase of Russian S-400 missile defenses, which it bought last year but has not yet fully deployed. Despite the threat of sanctions, it says the systems will ultimately be activated.

On Saturday, Erdogan also called on the European Union to increase its cooperation with Turkey in light of the support Ankara provided member states during the outbreak. “I hope the EU now understands that we are all in the same boat,” he said.

Turkey remains a candidate for EU membership but the process has long stalled amid disputes over Turkey’s human rights record, the handling of Syrian refugees, and gas exploration around Cyprus and the eastern Mediterranean.

PROBLEMS PERSIST

Foreign Minister Mevlut Cavusoglu said the aid initiative had lifted the mood with Washington.

“Has there been a positive atmosphere after the latest aid Turkey sent? Yes, and there is a positive atmosphere in the eyes of the (U.S.) public too,” Cavusoglu said, adding however that “the core problems with the United States still persist”.

Turkish aid shipments were also sent to Libya, Iraq, Iran, the Palestinian Authority, Russia, the Balkans and to China, where the new coronavirus first emerged.

Turkey says it has also sent aid to Israel, despite tensions over Israeli settlement building in the West Bank and the status of Jerusalem. Both sides expelled their top diplomats in 2018.

Turkey has sent aid to 15 countries in Africa, where it is seeking to expand influence and commercial ties.

Not all aid shipments have gone smoothly. A commercial shipment of ventilators to Spain was delayed over export licenses. Another commercial shipment of 400,000 protective suits to Britain was criticized after some failed quality checks, but both Ankara and London said that was not a government-to-government shipment, and that there had been no problem with aid sent directly by Turkey.

While the diplomatic outreach may have brought a change of tone to some of Ankara’s troubled international relations, analysts say lasting results are unlikely without concrete steps to address fundamental differences.

“No amount of goodwill, no amount of medical diplomacy will alter the negative repercussions that Turkey’s deployment of the S-400s has produced in Washington,” said Fadi Hakura, consulting fellow at the Royal Institute of International Affairs in London.

“If Turkey wants to curry favor with Washington, it has to terminate the S-400s.”

Gonul Tol, founding director of The Middle East Institute’s Center for Turkish Studies in Washington, said Turkey’s differences with the EU would also not be resolved overnight.

“While some countries have welcomed Turkish aid, Ankara’s problems with its neighbors and Western allies are too serious to be resolved by a few symbolic steps,” she said.

(Additional reporting by Dominic Evans; Editing by Daren Butler and Gareth Jones)

Over 80% of U.S. small businesses expect longer impact of pandemic: survey

By Andrea Shalal

WASHINGTON (Reuters) – Eighty-one percent of small U.S. companies surveyed by Veem, a global payments network, expect the new coronavirus pandemic to affect their business over the next 12-16 months, and nearly 90% are bracing for an economic slowdown, the company said Monday.

San Francisco-based Veem, which helped thousands of small companies apply for loans under the federal government’s $660 billion emergency Paycheck Protection Program (PPP), said small businesses were moving quickly to adapt to the changing climate.

Of the 690 firms surveyed, 65% said they had either submitted an application for the federal aid or planned to do so in the near future, Veem said in its first report on the sentiment among small to mid-sized businesses.

The Small Business Administration has so far approved more than 2.5 million loans totaling $536 billion, it said Friday.

The U.S. economy – the largest in the world – has been particularly hard hit by widespread shutdowns aimed at containing the spread of COVID-19, the disease caused by the coronavirus. U.S. government data on Friday showed the unemployment rate surging to 14.7% last month. The White House said joblessness could hit 20% in May.

The crisis was having a mixed impact on small businesses, said Veem chief executive Marwan Forzley, with some companies struggling to survive, while others benefited as their businesses were deemed essential or they switched to working online.

“When you look at the data, there’s surprising resiliency with these small and mid-sized businesses. Despite all the uncertainty, they’re trying to make changes in their businesses, to … either benefit from the situation or repurpose their business so that they’re not as badly impacted.”

Nearly 70% of the companies surveyed cited some uncertainty about the U.S. economy in 2020, and 55% said they had already experienced some significant impact to revenue.

About 30% of the companies were more optimistic, suggesting that some industries were better positioned to thrive in the current environment, Forzley said, citing online retailers and other e-commerce businesses.

More than half of the companies reported moderate to high supply-chain disruptions as a result of factory shutdowns, border restrictions and industry-wide furloughs, and more than one third said they were now setting up regional supply chains or rapidly pivoting their supply chain to make needed supplies.

Nearly one-quarter of the companies were investing in new technology or aligning their information technology systems.

Liquidity remained a “key pain point”, the survey showed, with 52% of companies cutting operational costs and 59% applying for loans, the survey showed. Only 13% said they had not taken any measures to prepare for a slowdown.

Nearly 54% of the companies said they were freezing hiring and 23% were downsizing staff, but nearly 18% said they planned to increase staff training and support.

(Reporting by Andrea Shalal. Editing by Gerry Doyle)

Rare syndrome tied to COVID-19 kills three children in New York, Cuomo says

By Nathan Layne

(Reuters) – Three children in New York have died from a rare inflammatory syndrome believed to be linked to the novel coronavirus, Governor Andrew Cuomo said on Saturday, a development that may augur a pandemic risk for the very young.

Both Cuomo and his counterpart in the neighboring state of New Jersey also spoke on Saturday about the pandemic’s growing toll on mental health, another factor on the minds of governors as they weigh the impact of mounting job losses against health risks in moving to loosen restrictions on daily life.

Nearly all of the 50 U.S. states will have taken steps to relax lockdown measures by this weekend, including states like Arizona and Mississippi, which are reporting increasing infections of COVID-19, the disease caused by the virus, highlighting the risk of a new wave of outbreaks.

Cuomo told a daily briefing that he was increasingly worried about a syndrome that shares symptoms with toxic shock and Kawasaki disease, which he said included inflammation of the blood vessels and potentially fatal damage to the heart.

He said three children – including a five-year old disclosed on Friday – have died from such symptoms while also testing positive for COVID-19 or related antibodies, suggesting a link that was still not fully understood.

Cuomo, who has emerged as a leading national voice on states’ response to the coronavirus crisis, said state health officials were reviewing 73 similar cases, which have rattled a prior assumption that children were largely not susceptible to the novel coronavirus.

“We are not so sure that is the fact anymore. Toddler, elementary school children are presenting symptoms similar to Kawasaki disease or toxic shock-like syndrome,” Cuomo said. “It’s very possible that this has been going on for several weeks and it hasn’t been diagnosed as related to COVID.”

Cuomo said state health officials had partnered with the New York Genome Center and the Rockefeller University to look at whether there is a genetic basis for the syndrome and have been asked by the federal Centers for Disease Control and Prevention to develop national criteria for identifying and treating cases.

The syndrome shares symptoms with toxic shock and Kawasaki disease, which is associated with fever, skin rashes, swelling of the glands, and in severe cases, inflammation of arteries of the heart. Scientists are still trying to determine whether the syndrome is linked with the new coronavirus because not all children with it have tested positive for the virus.

At a separate briefing, New Jersey Governor Phil Murphy said the death of a four-year old disclosed on Friday was not related to the syndrome. “This is a very specific situation with this blessed little kid and we are going to leave it at that.”

‘TOXIC MIX’

New York and New Jersey are at the epicenter of the pandemic in the United States, accounting for nearly half of the 77,737 American deaths from COVID-19, according to a Reuters tally, and the two states have among the strictest lockdown rules still in place.

They are also at the center of a devastating economic toll underscored in government data released on Friday showing the U.S. unemployment rate rose to 14.7% last month, up from 3.5% in February and shattering the post-World War Two record of 10.8% set in November 1982.

Cuomo said his state has seen increasing reports of mental health issues, substance abuse and domestic violence, all tied to the economic stress and isolation of the lockdowns.

On Friday a study released by the Well Being Trust and the American Academy of Family Physicians estimated an additional 75,000 people could lose their lives to suicide, drugs and other contributors to “deaths of despair” stemming from the crisis.

Murphy echoed those concerns.

“The cure for the health crisis is keeping people isolated,” Murphy told his briefing. “You add to that job loss, small businesses that have been crushed. It’s a toxic mix.”

Cuomo said 226 New Yorkers died from COVID-19 on Friday, up from 216 a day earlier, but less than half the levels recorded two weeks ago. He said hospitalizations and intubations continued their downward trend, further evidence the state has gained a measure of control over the virus.

Murphy said an additional 166 residents of his state had died over the past 24 hours from COVID-19, bringing its total fatalities to 9,116, while total cases rose by 1,759 to 137,085.

On a positive note, Murphy said the number of people hospitalized for the disease continued to fall, with the 422 patients discharged over the past 24 hours outpacing the 364 newly admitted for treatment.

Yet Murphy warned against complacency and said his constituents should continue to practice social distancing.

“We are not out of the woods, folks. Let’s not forget that,” he said.

(Reporting by Nathan Layne in Wilton, Connecticut; Editing by Daniel Wallis and Dan Grebler)

White House considers more coronavirus aid as jobs picture worsens

By David Morgan and Susan Heavey

WASHINGTON (Reuters) – The White House has begun informal talks with Republicans and Democrats in Congress about what to include in another round of coronavirus relief legislation, officials said on Sunday, while predicting further U.S. jobs losses in the coming months.

Officials in President Donald Trump’s administration, including Treasury Secretary Steven Mnuchin and White House economic adviser Larry Kudlow, said they were holding discussions with lawmakers on issues including potential aid to states whose finances have been devastated by the pandemic.

Another White House economic adviser, Kevin Hassett, said future legislation could include food aid to help Americans struggling with hunger amid widespread job losses that have ruined the finances of many people. It also could include broadband access for those who lack it, Hassett added.

While Democrats, who control the House of Representatives, are moving to unveil new legislation as early as this week, the White House signaled it is in no hurry to pass another relief bill.

“Let’s take the next few weeks,” Mnuchin told the “Fox News Sunday” program.

Since early March, Congress has passed bills allocating $3 trillion to combat the pandemic, including taxpayer money for individuals and companies to blunt an economic impact that includes an unemployment rate to 14.7% in April after U.S. job losses unseen since the Great Depression of the 1930s.

“We just want to make sure that before we jump back in and spend another few trillion of taxpayers’ money that we do it carefully,” Mnuchin said. “We’ve been very clear that we’re not going to do things just to bail out states that were poorly managed.”

Pressure for further action may mount as the near-term economic picture worsens.

On CBS’s “Face the Nation,” Hassett said the U.S. unemployment rate could rise to somewhere “north of 20 percent” in May or June before the economy moves into what administration officials have said will be a robust recovery in late 2020.

The April unemployment rate announced by the Labor Department undercounts some out-of-work Americans, economists say.

Asked if the country could now be facing a “real” unemployment rate of close to 25 percent, Mnuchin replied: “We could be.” Such a rate also includes people who have lost jobs and are not actively seeking employment and people considered underemployed.

IMMIGRATION ENFORCEMENT

Trump has previously threatened to withhold more coronavirus relief funds from states that limit cooperation with federal immigration enforcement – a stance critics said would exploit a public health crisis to advance political goals. Advisers said last week the White House would not consider new stimulus legislation in May.

Democrats are pushing for another massive relief bill that would include more money for state and local governments, coronavirus testing and the U.S. Postal Service.

“It’s not that we’re not talking. We are. It’s just informal at this stage,” Kudlow told ABC’s “This Week” program, referring to White House discussions with lawmakers.

“We’re collecting ideas for next steps, which will undoubtedly be data-driven,” Kudlow said.

Kudlow said he took part in a Friday conference call with House lawmakers from both parties, and plans to do the same on Monday with members of the Senate, which is controlled by Trump’s fellow Republicans.

“If we go to a phase-four deal, I think that President Trump has signaled that, while he doesn’t want to bail out the states, he’s willing to help cover some of the unexpected COVID expenses that might have come their way,” Hassett said on CNN’s “State of the Union.”

The White House is “absolutely” pushing for a payroll tax cut, Mnuchin said. Trump has called for a cut to the tax, which is paid by employers and workers and funds the social safety-net programs Social Security and Medicare. The proposal has garnered little congressional support.

White House predictions on the economy and how quickly a coronavirus vaccine could be rolled out were questioned on Sunday by both Democrats and Republicans.

The United States will need more tests before schools can reopen later in the year, said Republican Lamar Alexander, chairman of the Senate Health, Education, Labor and Pensions Committee.

Appearing on NBC’s “Meet the Press,” Alexander appeared to question the White House’s ability to meet a target of having 100 million vaccine doses by autumn and 300 million by the end of 2020. Alexander called it “an amazingly ambitious goal” and added, “I have no idea if we can reach that.”

No such vaccine for this pathogen has been approved though a number are under development.

Neal Kashkari, president and CEO of the Federal Reserve Bank of Minneapolis, told ABC’s “This Week” he would welcome a robust recovery.

“But that would require a breakthrough in vaccines, a breakthrough in widespread testing, a breakthrough in therapies, to give all of us confidence that it’s safe to go back,” Kashkari said. “I don’t know when we’re going to have that confidence.”

(Reporting by David Morgan, Susan Heavey and Heather Timmons; Writing by Heather Timmons; Editing by Lisa Shumaker, Daniel Wallis and Will Dunham)